Built on evidence of what works.

The structure and content of Canopie’s program comes from robust evidence and hundreds of interviews with expecting and new moms, experts, and health professionals.

Proven to work

Results from an initial randomized controlled trial indicate significant clinical improvements after only 2 weeks of engagement in the Canopie program.

75 percent
said they would refer a friend to the program
4.7 billion dollars
reported a positive change in emotional health
85 percent
of participants with possible symptoms of depression had a clinically significant change in their mood
Bar graph showing research results


79% of participants with symptoms of depression in the treatment group experienced a change in their EPDS depression score of greater than 4, surpassing the reliable change index.

The program was most effective for mothers with moderate to severe symptoms of depression.

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Our study showed a treatment effect size hedges (g) of 0.68 (p=.00015, n=100), compared to in-person CBT effect size 0.642.

There was no difference in effect size across income, culture, race, or age.

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Line graph showing the clinical significance of the treatment vs. control.

Supporting research

Over 50 randomized control trials have demonstrated significant treatment effects from therapeutic techniques such as CBT, IPT and CFT delivered in a similar way to the Canopie program, both guided self-help and pure self-help, including the below.

The Effectiveness of a Guided Internet-Based Tool for the Treatment of Depression and Anxiety in Pregnancy (Mamakits Online): RCT

Heller, H. M., Hoogendoorn, A. W., Honig, A., Broekman, B. F., & van Straten, A.
Journal of Medical Internet Research

Delivering the Thinking Healthy Programme for Perinatal Depression through Volunteer Peers: A Cluster RCT in Pakistan.

Sikander, Siham, et al.
The Lancet Psychiatry

Netmums: A Phase II RCT of a Guided Internet Behavioural Activation Treatment for Postpartum Depression.

O'Mahen, H. A., Richards, D. A., Woodford, J., Wilkinson, E., McGinley, J., Taylor, R. S., & Warren, F. C.
Psychological Medicine

A Proof-of-Concept Pilot RCT of Brief Internet-Based CMT and CBT for Perinatal and Intending to Become Pregnant Women.

Kelman A. , Evare B. S., Barrera A. Z., Muñoz R. F., Gilbert P.
Clinical Psychology & Psychotherapy

A RCT of Therapist-Assisted, Internet-Delivered Cognitive Behavior Therapy for Women with Maternal Depression.

Pugh, N. E., Hadjistavropoulos, H. D., & Dirkse, D.

Online Prevention of Postpartum Depression for Spanish- and English-Speaking Pregnant Women: A Pilot RCT.

Barrera A. Z., Robert E Wickham R. E., Muñoz R. F.
Internet Interventions

RCT to Prevent Postpartum Depression in Mothers on Public Assistance

Zlotnick C., Tzilos G., Miller I., Seifer R. and Stoute R.
Journal of Affective Disorders

Policy recommendations

U.S. and U.K. government reviews recommend the used of Cognitive Behavioral Therapy and Interpersonal Therapy to prevent and treat perinatal depression.

Antenatal and postnatal mental health: clinical management and service guidance

National Institute for Health and Care Excellence

Interventions to Prevent Perinatal Depression: U.S. Preventative Services Task Force Recommendation Statement

U.S. Preventative Task Force

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